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Gene Editing
The core mechanism of gene editing involves introducing a specific, double-strand break in the DNA helix at a targeted location, which the cell then attempts to repair.
Scientists can leverage the cell's natural repair mechanisms to either disable a faulty gene or insert a desired sequence. The newest iterations of this technology, such as prime editing, aim to make single-base changes without the error-prone double-strand break, significantly enhancing the safety and precision of the tool. However, even with improved precision, the sheer complexity of the genome—where non-coding regions play vital regulatory roles—means unintended effects remain a risk.
Preclinical studies are heavily focused on minimizing these 'off-target' edits, using advanced sequencing methods to ensure the edits are clean and confined to the intended location. For many rare genetic conditions, where conventional treatments are limited or non-existent, gene editing offers a cure, not just a treatment, fundamentally changing…








https://www.forbes.com/sites/forbestechcouncil/2022/02/17/market-trends-and-predictions-for-2022/?sh=3777817c66d7